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In an attempt to explain the states of the disease and health, Hippocrates defined the existence of four principal fluids of/in the body. They were blood, phlegm, black bile and yellow bile. He also suggested that there were four elemental conditions — cold, hot, dry and moist — and that a state of health existed when these four fluids and qualities were in balance. Disruption in/of the natural balance would result in disease; for example, too much phlegm made the body too cold and too wet.